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Publicaties Prof. Karin Roelofs

Enter D, Spinhoven P, Roelofs K. (in press). Dare to approach: single dose testosterone administration promotes threat approach in social anxiety disorder. Clinical Psychological Science.

Volman I, von Borries AK, Bulten BH, Verkes RJ, Toni I, Roelofs K (2016). Testosterone Modulates Altered Prefrontal Control of Emotional Actions in Psychopathic Offenders. eNeuro, Online Journal of the Society for Neuroscience 3(1) e0107-15.2016 1–12

Radke S, Volman I, Mehta P, van Son V,  Enter D, Sanfey A, Toni I, de Bruijn E,  Roelofs K. (2015) Testosterone biases the amygdala towards social threat approach. Science Advances, 1:e1400074

Lojowska M, Gladwin TE, Hermans EJ, Roelofs K. (2015). Freezing promotes perception of coarse visual features. J Exp Psychol Gen. 144(6):1080-8. doi: 10.1037/xge0000117.

Niermann HC, Ly V, Smeekens S, Figner B, Riksen-Walraven JM, Roelofs K. (2015). Infant attachment predicts bodily freezing in adolescence: evidence from a prospective longitudinal study. Front Behav Neurosci. 12;9:263. doi:10.3389/fnbeh.2015.00263.

Kret ME, Stekelenburg JJ, de Gelder B, Roelofs K. (2015). From face to hand: Attentional bias towards expressive hands in social anxiety. Biol Psychol. S0301-0511(15)30090-9. doi: 10.1016/j.biopsycho.2015.11.016

Enter D, Terburg D, Harrewijn A, Spinhoven P, Roelofs K. (2015). Single dose testosterone administration alleviates gaze avoidance in women with Social Anxiety Disorder. Psychoneuroendocrinology. 63:26-33. Doi 10.1016/j.psyneuen.2015.09.008.

Cremers H,  Veer I, Spinhoven P,  Rombouts S,  Yarkoni T, Wager TD, Roelofs K. (2015). Frontal-amygdala decoupling during public speech anticipation stress in patients with social anxiety disorder. Psychol Medicine, 45(7):1521-9.

Cremers H,  Veer IM, Spinhoven P,  Rombouts S,  Roelofs K. (2015) Neural sensitivity to social punishment versus reward anticipation in Social Anxiety Disorder. Frontiers Beh. Neuroscience, 8:439.

Mehta P, van Son V, Welker K, Prasad S, Sanfey A, Smidts A, Roelofs K. (In Press). Exogenous Testosterone in Women Enhances and Inhibits Competitive Decision-Making Depending on Victory-Defeat Experience and Trait Dominance.Psychoneuroendocrinology.

Van Der Schaaf ME, Schmits IC, Roerink M, Geurts DE, Toni I, Roelofs K, ea. (2015). Investigating neural mechanisms of change of cognitive behavioural therapy for chronic fatigue syndrome: a randomized controlled trial. BMC Psychiatry.15:144.

Hagenaars M, Oitzl M, Roelofs K. (2014). Updating freeze: Aligning animal and human research. Neuroscience & Biobehavioral Reviews, 47:165-76.

Ly V, Hyus Q, Stins, J, Roelofs, K. Cools R. (2014). Individual differences in bodily freezing predict emotional biases in decision making. Front Behav Neurosci. 8, 237.

Smeets-Janssen M, Roelofs K, van Pelt J, Spinhoven, P. Zitman F, Penninx B Giltay E. (2014). Salivary testosterone is consistently and positively associated with extraversion: Results from the Netherlands Study of Depression and Anxiety.Neuropsychobiology

Brown E, Tas C, Kuzu D, Esen-Danaci A, Roelofs K, Brüne M. (2014). Social approach and avoidance behaviour for negative emotions is modulated by endogenous oxytocin and paranoia in schizophrenia. Psychiatry Res. 

Enter D, Spinhoven P, Roelofs K. (2014). Alleviating social avoidance: Effects of single dose testosterone administration on approach-avoidance action. Hormones and Behavior, 4: 351-354.  

Stins JF, Lobel A, Roelofs K, Beek PJ. (2014). Social embodiment in directional stepping behavior. Cogn Process, 3, 245-252.

Kret ME, Roelofs K, Stekelenburg JJ, de Gelder B. (In press). Emotional signals from faces, bodies and scenes influence observers' face expressions, fixations and pupil-size. Front Hum Neurosci. 

Ly V, Cools R, Roelofs K. (2014) Aversive disinhibition of behavior and striatal signaling in social avoidance. SCAN,10:1530-1536. 

Volman I, Verhagen L, den Ouden HE, Fernández G, Rijpkema M, Franke B, Toni I, Roelofs K. (2013). Reduced serotonin transporter availability decreases prefrontal control of the amygdala. J Neurosci. 33(21):8974-9. 

Van Strien T, Roelofs K, de Weerth, C. (2013) Cortisol reactivity and distress-induced emotional eating.Psychoneuroendocrinology 5,677-84.

Fouche JP, van Der Wee NJ, Roelofs K, Stein DJ (2013). Recent advances in the brain imaging of social anxiety disorder. Hum Psychopharmacol (1):102-5. 

Radke, S. Roelofs, K. de Bruijn E (2013). Acting on anger: social anxiety modulates approach-avoidance tendencies after oxytocin administration. Psych Science, 24(8):1573-8. 

Hagenaars M, Stins J. Roelofs K. (2013). Human freezing in response to affective films. Anxiety, Stress, & Coping, 27(1):27-37. 

Boksem M, Mehta P, Van den Bergh B, van Son V, Trautmann S, Roelofs K, Smidts A, Sanfey A (2013). Testosterone inhibits trust, but promotes reciprocity Psych Science, 24(11):2306-14. 

Kret M, Stekelenburg J, Roelofs K, de Gelder B. (2013) Perception of face and body expressions using electromyography, pupillometry and gaze measures. Front Psychol. 4:28.

Volman I, Roelofs K, Koch S, Verhagen L, Toni I. (2012). Anterior Prefrontal Cortex Inhibition Impairs Control over Social Emotional Actions. Curr Biol. 21(20):1766-70. 

Hermans E. Henckens M. Roelofs K. Fernández G. (2012). Fear bradycardia and activation of the human periaqueductal grey.Neuroimage, 66C:278-287.

Enter D, Colzato LS, Roelofs K. (2012). Dopamine transporter polymorphisms affect automatic social approach-avoidance tendencies. Genes, Brain and Behav, 11(6):671-6.

Hagenaars MA, Stins JF, Roelofs K. (2012). Aversive life events enhance human freezing responses. J Exp Psychol Gen. 141(1):98-105.

Giltay E, Enter D, Zitman F, Penninx B, van Pelt J, Spinhoven P, Roelofs K (2012). Salivary testosterone: associations with anxiety disorders, and antidepressant use in a large cohort study, J Psychosom Res 72(3):205-213. 

Von Borries AKL, Volman I, de Bruijn ERA, Bulten BH, Verkes RJ, Roelofs K. (2012). Psychopaths lack the automatic avoidance of social threat: relation to instrumental aggression. Psychiatry Res,2-3):761-6.

Spinhoven P, Elzinga BM, Hovens JG, Roelofs K, van Oppen P, Zitman FG, Penninx BW. 2011. Positive and negative life events and  personality traits in predicting course of depression and anxiety. Acta Psychiatr Scand. 124(6):462-73.  

Cremers H, van Tol M, Roelofs K. ea (2011). Extraversion is linked to volume of the orbitofrontal cortex and amygdala. PloS ONE.6(12):e28421.

Volman I, Toni I, Verhagen L, Roelofs K. (2011). Endogenous testosterone modulates prefrontal-amygdala connectivity during social emotional behavior. Cereb Cortex. 21(10):2282-90.

Putman P, Roelofs K. (2011). Effects of single cortisol administrations on human affect reviewed: Coping with stress through adaptive regulation. Psychoneuroendocrinology. 36(4):439-48. 

Bakvis P, Spinhoven P, Zitman FG, Roelofs K. (2011). Automatic avoidance tendencies in patients with psychogenic non epileptic seizures. Seizure. 20(8), 628-34.

Stins JF, Roelofs K, Villan J, Kooijman K, Hagenaars MA, Beek PJ. (2011). Walk to me when I smile: emotional faces modulate whole-body approach-avoidance behaviors. Exp Brain Res. 212(4):603-11. 

Spinhoven P, Elzinga B, Roelofs K, Hovens JG, van Oppen P, Zitman FG, Penninx BW. (2011). The effects of neuroticism, extraversion, and positive and negative life events on a one-year course of depressive symptoms in euthymic previously depressed patients versus healthy controls. J Nerv Ment Dis. 199(9):684-9. 

Roelofs K, Hagenaars MA, Stins J. (2010). Facing freeze: social threat induces bodily freeze in humans. Psych Science. 21(11):1575-81. 

Bakvis P, Spinhoven P, Putman P, Zitman FG, Roelofs K. (2010). The effect of stress induction on working memory in patients with psychogenic nonepileptic seizures. Epilepsy Behav. 19(3):448-54. 

Voon V, Brezing C, Gallea C, Ameli R, Roelofs K, LaFrance WC Jr, Hallett M. (2010). Emotional stimuli and motor conversion disorder. Brain. 133:1526-36. 

Cremers HR, Demenescu LR, Aleman A, Renken R, Tol M, vd Wee N,  Veltman D, Roelofs K. (2010). Neuroticism modulates amygdala-prefrontal connectivity in response to negative emotional facial expressions. Neuroimage. 49(1):963 70. 

de Lange FP, Toni I, Roelofs K. (2010). Altered connectivity between prefrontal and sensorimotor cortex in conversionparalysis.Neuropsychologia. 48(6):1782-8. 

Roelofs K, Putman P, Schouten S, Lange WG, Volman I, Rinck M. (2010). Gaze direction differentially affects avoidance tendencies to happy and angry faces in socially anxious ind. Beh Res Ther. 48(4):290-4. 

Bakvis P, Spinhoven P, Giltay EJ, Kuyk J, Edelbroek PM, Zitman FG, Roelofs K. (2010). Basal hypercortisolism and trauma in patients with psychogenic nonepileptic seizures. Epilepsia. 51(5):752-9.

van Peer JM, Spinhoven P, Roelofs K. (2010). Psychophysiological evidence for cortisol-induced reduction in early bias for implicit social threat in social phobia. Psychoneuroendocrinology. 35(1):21-32. 

Elzinga BM, Spinhoven P, Berretty E, de Jong P, Roelofs K. (2010). The role of childhood abuse in HPA-axis reactivity in Social Anxiety Disorder: a pilot study. Biol Psychol. 83(1):1-6. 

Van Peer J, Rotteveel M, Spinhoven P, Tollenaar M, Roelofs K (2010). Affect-congruent movements of happy and angry faces facilitate affect categorization. Cogn Emotion. 24(5), 863-875.

Spinhoven P, Elzinga BM, Hovens JG, Roelofs K, Zitman FG, van Oppen P, Penninx BW. (2010). The specificity of childhood adversities and negative life events across the life span to anxiety and depressive disorders. J Affect Disord. 126(1-2):103-12.

Roelofs K, Minelli A, Mars RB, van Peer J, Toni I. (2009). On the neural control of social emotional behavior. Soc Cogn Affect Neurosci. 4(1):50-8. 

Roelofs K, van Peer J, Berretty E, Jong P, Spinhoven P, Elzinga BM. (2009). HPA-axis hyperresponsivity is associated with increased social avoidance in social phobia. Biol Psychiatry. 15;65(4):336-43. 

Ly V, Roelofs K. (2009). Social anxiety and cognitive expectancy of aversive outcome in avoidance conditioning. Behav Res Ther. 47(10):840-7. 

van Peer J, Spinhoven P, van Dijk J, Roelofs K. (2009). Cortisol-induced enhancement of emotional face proc. in social phobia depends on symptom sev. and motivational context. Biol Psychol. 81(2):123-30. 

Bakvis P, Roelofs K, Kuyk J, Edelbroek P, Swinkels W, Spinhoven P. (2009). Trauma, stress, and preconscious threat processing in patients with psychogenic nonepil seizures. Epilepsia. 50(5):1001-11. 

Bakvis P, Spinhoven P, Roelofs K. (2009). Basal cortisol is positively correlated to threat vigilance in patients with psychogenic nonepileptic seizures. Epilepsy Behav. 16(3):558-60. 

de Lange FP, Roelofs K, Toni I. (2008). Motor imagery: a window into the mechanisms and alterations of the motor system. Cortex. 44(5):494-506. 

van Peer JM, Roelofs K, Spinhoven P. (2008). Cortisol administration enhances the coupling of midfrontal delta and beta oscillations. Int J Psychophysiol. 67(2):144-50. 

Elzinga BM, Roelofs K, Tollenaar MS, Bakvis P, van Pelt J, Spinhoven P. (2008). Diminished cortisol responses to psychosocial stress associated with adverse events. Psychoneuroendocrinology. 33:227-37. 

Reedijk WB, van Rijn MA, Roelofs K, Tuijl JP, Marinus J, van Hilten JJ. (2008). Psychological features of patients with complex regional pain syndrome type I related dystonia. Mov Disord. 23(11):1551-9. 

van Peer J, Roelofs K, Rotteveel M, van Dijk J, Spinhoven P, Ridderinkhof R. (2007). The effects of cortisol adm. On approach-avoidance behavior: an event-related potential study. Biol Psychol. 76(3):135-46. 

Roelofs K, Spinhoven P. (2007). Trauma and medically unexplained symptoms towards an  integration of cognitive and neuro-biological accounts. Clin Psychol Rev. 27(7):798-820. 

de Lange FP, Roelofs K, Toni I. (2007). Increased self-monitoring during imagined movements in conversion paralysis. Neuropsychologia. 15;45(9):2051-8.  

Roelofs K, Bakvis P, Hermans EJ, van Pelt J, van Honk J. (2007). The effects of social stress and cortisol responses on the preconscious selective attention to social threat. Biol Psychol.  75(1):1-7. 

Roelofs K, de Bruijn ER, Van Galen GP. (2006). Hyperactive action monitoring during motor-initiation in conversion paralysis: an event-related potential study. Biol Psychol. 71(3):316-25. 

Hagenaars MA, Roelofs K, Hoogduin K, Van Minnen A. (2006). Motor and sensory dissociative phenomena associated with induced catalepsy: A brief communication. Int J Clin Exp Hypn. 54(2):234-44.

Roelofs K, Elzinga BM, Rotteveel M. (2005). The effects of stress-induced cortisol responses on approach-avoidance behavior. Psychoneuroendocrinology. 30(7):665-77. 

Elzinga BM, Roelofs K. (2005). Cortisol-induced impairments of working memory require acute sympathetic activation. Behav Neurosci. 119(1):98-103. 

Roelofs K, Spinhoven P, Sandijck P, Moene FC, Hoogduin KA. (2005). The impact of early trauma and recent life-events on symptom severity in patients with conversion d. J Nerv Ment Dis 193(8):508-14. 

Spinhoven P, Roelofs K, Moene F, Kuyk J, Nijenhuis E, Hoogduin K, Van Dyck R. (2004). Trauma and dissociation in conversion disorder and chronic pelvic pain. Int J Psychiatry Med. 34(4):305-18.

Roelofs K, van Galen GP, Eling P, Keijsers GP, Hoogduin CA. (2003). Endogenous and exogenous attention in patients with conversion paresis. Cogn Neuropsychol. 20(8):733-45. 

Roelofs K, Keijsers GP, Hoogduin KA, Näring GW, Moene FC. (2002). Childhood abuse in patients with conversion disorder. Am J Psychiatry. 159(11):1908-13. 

Roelofs K, Hoogduin KA, Keijsers GP, Näring GW, Moene FC, Sandijck P. (2002). Hypnotic susceptibility in patients with conversion disorder. J Abnorm Psychol. 390-5. 

van Minnen A, Wessel I, Dijkstra T, Roelofs K.(2002). Changes in PTSD patients' narratives during prolonged exposure therapy: a replication and extension. J Trauma Stress. 15(3):255-8. 

Roelofs K, van Galen GP, Keijsers GP, Hoogduin CA. (2002). Motor initiation and execution in patients with conversion paralysis. Acta Psychol 110(1):21-34. 

Roelofs K, Näring GWB, Keijsers GPJ, Hoogduin CAL, Van Galen GP, Maris E. (2001). Motor imagery in conversion paralysis.Cognitive Neuropsychiatry, 6(1), 21-40.  

Näring, G.W.B., Roelofs, K., & Hoogduin, C.A.L. (2001). The Stanford Hypnotic Susceptibility Scale, Form C: Normative data of a Dutch Student Sample. International Journal of Clinical and Experimental Hypnosis, 49(2), 139-145.  

Moene, F.C., Spinhoven, Ph., Hoogduin, C.A.L., Sandijck, P., & Roelofs, K. (2001). Hypnotizability, dissociation and trauma in patients with a conversion disorder: an exploratory study. Clinical Psychology and Psychotherapy, 8, 400 410. 

Roelofs, K., Hoogduin, C.A.L., & Keijsers, G.P.J. (2002). Motor imagery in hypnotic paralysis. International Journal of Clinical and Experimental Hypnosis, 50(1), 51-66.

Roelofs K, Näring GW, Moene FC, Hoogduin CA. (2000). The question of symptomlateralization in conversion disorder. J Psychosom Res. 49(1):21-5. 

Roelofs K, Wolters P. Fernandez-Carol C, Vlught Hvd, Moss H, Brouwers P. (1996). Impairments in expressive emotional language in children with symptomatic HIV infection: relation with brain abnormality and immune function. J Int Neuropsychology Soc:2:193. 


Books (or contributions to books)

Roelofs K & Passman (in press) Trauma, stress and cognitive functions in conversion disorder. In I. Hallett, Stone, Carson. Handbook of Neurology: Psychogenic movement disorders. Elsevier, UK.

Klaassen R, van Minnen A, Roelofs K. (2015). Conversiestoornis. In I. Franken, P. Muris & D. Denys. Handboek Psychopathologie. Tweede druk. De Tijdstroom Utrecht.

Roelofs K (2013) Automatische emotionele responsen onderdrukken. In I. Franken. Hersenwerk in uitvoering. Mediaalert, Amersfoort. Pp 62-70.

Van Beilen M, Roelofs K. (2013). Conversion disorders. In Cognitive Neuropsychiatry: A Aleman, P Eling, L Krabbendam. Boom, The Netherlands. pp 219-240.

Klaassen R, van Minnen A, Roelofs K. (2013). Conversiestoornis. In I. Franken, P. Muris & D. Denys. Handboek Psychopathologie.De Tijdstroom Utrecht, pp 473-483.

Roelofs K. (In Press). Aandachtsprocessen bij de conversiestoornis. In F. Moene et al. Onverklaarde Lichamelijk Klachten COLK. Yulius Academy, Netherlands.

Roelofs K. (2012). Hersenen op de vlucht. Het angstige brein in actie. (2012). Radboud University Press p1-26.

Roelofs K, Toni I, De Lange F. (2011). Action control in conversion paralysis: evidence from motor imagery. In: Hallett et al,Psychogenic Movement Disorders and Other Conversion Disorders, pp. 160-167. Cambridge University Press.

Bakvis P, Roelofs K. (2011). Basal cortisol and threat vigilance in patients with psychogenic-non-epileptic-seizures (PNES). In: Hallett et al, Psychogenic Movement Disorders and Other Conversion Disorders, pp. 187-188. Cambridge University Press.

Roelofs K, Spinhoven P. (2010). Conversion. In: Weiner, I.B. & Graighead, W.E. (Eds.), The Corsini Encyclopedia of Psychology (4th edition), 407-410. Hoboken, New Jersey: John Wiley & Sons, Inc.

Moene FC, Roelofs K. (2008). Hypnosis in the treatment of conversion and somatization disorder. In M.R. Nash & A.J. Barnier (Eds), The Oxford Handbook of Hypnosis. Theory, Research and Practice (pp. 625-645). Oxford: Oxford University Press.

Roelofs K. (2005). A cognitive account on conversion and somatization disorder; commentary on Merskey and Mai Somatization and conversion disorders: a review. In Maj, M. Akiskal, H.S. Mezzich, J.U. Okasha, A.: "Somatoform Disorders" (vol. 9 of the WPA series "Evidence and Experience in Psychiatry").

Roelofs K. (2003). De conversieverlamming: Neuropsychologische theorieen en empirische ondersteuning. In: Op het Grensvlak van Neurology en Psychiatrie. p49-54.(ISBN 903730659 4).

Näring G, Roelofs K, Prime W, Mulders D, Hoogduin C. (2002). The Stanford Hypnotic Susceptibility Scale, Form C: Preliminary norms for  students. In C.A.L. Hoogduin, C.P.D.R. Schaap & H.A.A. De Berk (Eds.). Issues on Hypnosis, Zeist: Cure & Care, pp.65-69.

Spinhoven P,  Elzinga B, Roelofs K. (2002). Theoretische modellen van PTSS In A. van Minnen & M. Verbraak: Psychologische interventies bij posttraumatische stressstoornis, Zeist, Cure & Care development.

Roelofs K, Näring GWB, Hoogduin CAL, Moene FC, Sandijck P. (2002). Dissociative symptoms and hypnotic susceptibility in conversion disorder, preliminary results. In: C.A.L. Hoogduin, C.P.D.R. Schaap & H.A.A. De Berk (Eds.). Issues on Hypnosis, Zeist: Cure & Care, pp 95-102.

Hoogduin C,  Roelofs K. (2001). Conversion disorders. In G. Burrows, R. Stanley, & P. Bloom. International Handbook of Clinical Hypnosis (pp.159-170). New York: Wiley.

Hoogduin C, Moene FC,  Roelofs K. (2001). Een behandelmodel voor conversie. In Ph Spinhoven, TK Bouman,  CAL

Hoogduin (eds.). Behandelstrategieën bij Somatoforme Stoornissen (pp.98-113). Houten: Bohn Stafleu Van Lochum.

Hoogduin C, Roelofs K,  Moene FC (1999). Over oorzaken en behandeling van conversieve fluisterspraak (afonie). In G. Hendriks (ed.), Een veilige plek voor angst. Evidence based behandeling voor angststoornissen (pp. 22-28). Zeist: Cure &Care.

Hansen, A., Roelofs, K., Keijsers, G.P.J., & Hoogduin, C.A.L (1997). Exposure and response prevention in the treatment of obsessions. Directieve therapie, 4, 308-325.


Prof. Karin Roelofs